Accelerating Discovery

With the aim of providing additional information related to our lab publications, here we have generated a data repository were full scans of Western blots and agarose gels are provided. This will help our colleagues troubleshooting antibodies and also observing raw data of cropped gels.

Rodriguez D., et al. (2012). BH3-only proteins are part of a regulatory network that control the sustained signaling of the Unfolded Protein Response sensor IRE1.  EMBO J. 31(10):2322-35. *#

Vidal R., et al. (2012). Targeting the UPR transcription factor XBP1 protects against Huntington’s disease through the regulation of FoxO1 and autophagy. Hum. Mol. Gen. 21(10):2245-62. *#

Rojas-Rivera D., et al. (2012). TMBIM3/GRINA is a novel Unfolded Protein Response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis. Cell Death Diff. 9:1013-26. *#

Zamorano S., et al. (2012). A BAX/BAK and Cyclophilin D-independent Intrinsic Apoptosis Pathway. PLoS One :e37782. *#

Valenzuela V, et al. (2012). Activation of the Unfolded Protein Response enhances motor recovery after spinal cord injury. Cell Death Dis. 3, e272 *#

Torres M., et al. (2012). Altered Prion protein expression pattern in CSF as a biomarker for  Creutzfeldt-Jakob Disease. PLoS One .7:e36159. *#

Castillo K, et al. (2011). BAX inhibitor-1 regulates autophagy by controlling the IRE1/JNK branch of the unfolded protein response. EMBO J. 4465-78*#

Torres M., et al. (2010). Prion Protein Misfolding Affects Calcium Homeostasis and Sensitizes Cells to Endoplasmic Reticulum Stress. PlosOne. 5: e15658- e15658.*#

Hetz C., et al. (2009). XBP-1 deficiency in the nervous system protects against amyotrophic lateral  sclerosis by increasing autophagy.  Genes & Dev. 23:2294–2306

Lisbona F., et al. (2009). BAX Inhibitor-1 is a negative regulator of the ER stress sensor IRE1. Mol. Cell. 33:679-691.*#